Easy Bruising? Beware Of Autoimmune Disorders ITP
ITP is defined as an autoimmune disease that causes the number of platelets (thrombocytopenia/platelets) is a low, isolated with normal bone marrow and the absence of other causes of thrombocytopenia. This causes a characteristic rash or bruising and bleeding.Platelets are blood cells that assist in blood clotting to prevent and stop the bleeding. Platelets are normally in the range of 150,000 – 450,000/mm3.
Easy Bruising? Beware Of Autoimmune Disorders ITP |
Two different ITP clinical syndrome manifests as acute conditions in children and chronic conditions in adults. The acute form is often followed by infection and have spontaneous resolution within two months. Chronic ITP continues over six months with the specific cause is unknown.
Diagnosis of ITP is seen from a low number of platelets in a blood test (blood test). However, because the diagnosis also depends on other causes, additional investigations (such as a bone marrow biopsy) may be necessary in some cases.
In mild cases, careful observation may be necessary but it's a very low number of platelets or significant bleeding will probably require treatment with corticosteroids, intravenous imunoglobulin, anti-D immunoglobulin, or immunosuppressive drugs.
Platelet transfusions may be done but sometimes the body compensates by forming large abnormal platelets.
No comments: